Rosen 28

Description

Indication

Acne, Oral contraception, Premenstrual dysphoric disorder.

Administration

May be taken with or without food.Take dose at the same time each day. Women should be instructed to take the tablets→ Show more

Adult Dose

Contraception1 active tablet (3 mg drospirenone/0.03 mg EE) PO qDay for 21 days, THEN 1 inert tablet PO qDay for→ Show more

Child Dose

Contraception <14 years: Safety and efficacy not established >14 years: Same dosing as adult

Renal Dose

Renal impairment: CrCl (ml/min) <50 Avoid use.

Contraindication

Pregnancy. Undiagnosed abnormal genital bleeding. Renal insufficiency, hepatic dysfunction or tumor. Adrenal insufficiency,→ Show more

Mode of Action

Ethinylestradiol is a synthetic oestrogen while drospirenone is a progestogen with antimineralocorticoid and→ Show more

Precaution

May increase risk of breast cancer, thromboembolism and glucose intolerance. May lead to hyperkalaemia in patients with→ Show more

Side Effect

>10%Premenstrual syndrome (13.2%),Migraine/headache (10.7%)1-10%Breast pain/discomfort/tenderness (8.3%),Menstrual→ Show more

Pregnancy Category Note

Pregnancy category: XLactation: Small amounts of steroids are excreted in breast milk; estrogens may reduce→ Show more

Interaction

Increased risk of hyperkalaemia when used with ACE inhibitors, angiotensin II receptor antagonists, aldosterone→ Show more